Improving early detection and monitoring of hip bone disease in young patients
Official title: Early Detection and Monitoring of Osteonecrosis of the Femoral Head
Funded at University of Minnesota · NIH-11020995 · Data updated 2026-11-12
This study is looking at a serious hip problem called osteonecrosis of the femoral head (ONFH) that can affect young people, and it aims to find better ways to spot and track the condition early using advanced MRI scans, so that we can help prevent it from getting worse and improve treatment outcomes for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | March 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $586,094 |
| NIH project number | 5R01AR081877-03 |
| Project ID | NIH-11020995 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and young adults diagnosed with early-stage osteonecrosis of the femoral head.
✕Less likely to help
Patients with advanced ONFH or those who have already undergone hip replacement surgery may not benefit from this research.
What this research studies
This research focuses on osteonecrosis of the femoral head (ONFH), a serious hip condition that can lead to severe complications like hip replacement in young patients. The study aims to enhance early detection and monitoring of ONFH using advanced MRI techniques that can better assess bone health and treatment response. By improving imaging methods, the research seeks to prevent the progression of this disease and improve clinical outcomes for affected individuals. The approach involves characterizing how sensitive these new imaging techniques are in detecting early-stage ONFH and measuring the extent of bone damage and recovery.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more effective treatment options for patients with osteonecrosis of the femoral head.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for similar conditions, indicating potential for success in this approach.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Johnson, Casey Peter — University of Minnesota
- Study coordinator: Johnson, Casey Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.