Improving early autism screening in toddlers

Sensitivity of toddler screening: Integrating concurrent and prospective strategies to detect ASD

NIH-funded research Drexel University · NIH-11318946

Researchers will re-screen children who had autism checks as toddlers to find any cases that were missed so they can get help sooner.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDrexel University NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11318946 on NIH RePORTER

What this research studies

This project will contact families from three earlier toddler screening efforts and recheck children who either screened negative, screened positive but were lost to follow-up, or were evaluated and not diagnosed. The team will use standardized follow-up screening and clinical confirmation to look for children who may have been missed during routine well-child visits. By comparing initial screening results with these prospective detections, researchers aim to measure how often autism was overlooked and why. The work focuses on practical follow-up methods that could be used in community pediatric settings.

Who could benefit from this research

Good fit: Toddlers and young children who took part in prior pediatric autism screening programs — especially those who screened negative, were lost to follow-up, or were evaluated but not diagnosed — are the ideal participants.

Not a fit: Children who never had toddler autism screening, adults, or families who cannot be reached for follow-up are unlikely to be helped directly by this project.

Why it matters

Potential benefit: If successful, the project could lead to more timely autism diagnoses and earlier access to therapy for children who were previously missed.

How similar studies have performed: Previous universal screening programs have helped lower the age of autism diagnosis and reduce disparities, but few studies have done the kind of prospective re-screening of initially negative toddlers that this project will use.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.