Improving drug discovery by simplifying chemical reactions
Official title: Assessing Ligand vs Ligandless Catalysis to Simplify Chemical Transformations and Drug Discovery
Funded at Florida Gulf Coast University · NIH-10201920 · Data updated 2026-11-12
This study is all about finding new ways to make medicines that can fight stubborn bacteria that don't respond to regular drugs, and it's also a great opportunity for college students to learn and practice real science while using safe and eco-friendly materials.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida Gulf Coast University NIH-funded |
| Lab location | 1 site (Fort Myers, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2025 |
| Funding year | 2021 |
| Award (this year) | $396,626 |
| NIH project number | 1R15GM141726-01 |
| Project ID | NIH-10201920 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients suffering from infections caused by drug-resistant bacteria would be ideal candidates to benefit from this research.
✕Less likely to help
Patients with conditions that do not involve bacterial infections may not receive any benefit from this research.
What this research studies
This research focuses on developing new methods for creating therapeutic molecules that can combat drug-resistant bacteria. By using innovative catalysts made from two different transition metals, the project aims to simplify the chemical processes involved in drug synthesis. The research also provides undergraduate students with hands-on experience in scientific research, enhancing their skills in planning and executing experiments. The goal is to create small molecules from readily available materials while using environmentally friendly reagents like water and air.
Why it matters
Potential benefit: If successful, this research could lead to faster and more efficient development of new drugs to treat infections caused by resistant bacteria.
How similar studies have gone: Other research has shown promise in using innovative catalytic methods for drug discovery, indicating that this approach could lead to significant advancements.
Where this research is happening
-
Florida Gulf Coast University
Fort Myers, United States Active
Researchers
- Principal investigator: Bugarin, Alejandro — Florida Gulf Coast University
- Study coordinator: Bugarin, Alejandro
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.