NIH-funded research Sbir 1 grant

Improving drug development for rare cancers using a new testing method

Official title: Reimagining Pharmaceutical Drug Development in Oncology with a Biomimetic Platform

Funded at Teo Therapeutics Incorporated · NIH-10920344 · Data updated 2026-11-12

This study is working on a faster and cheaper way to develop new drugs for rare cancers that don’t have good treatments yet, using a special lab method that helps find promising options more quickly without needing a lot of animal testing.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionTeo Therapeutics Incorporated
NIH-funded
Lab location1 site (Beaverton, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$270,428
NIH project number1R43OD037620-01
Project IDNIH-10920344 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with rare cancers who have limited treatment options available.

Less likely to help

Patients with common cancers or those who do not have a diagnosis of cancer may not benefit from this research.

What this research studies

This research focuses on creating a more efficient process for developing drugs specifically for rare cancers that currently lack effective treatments. By utilizing a novel biomimetic platform, the researchers aim to streamline the early stages of drug development, allowing for quicker identification of promising drug candidates. The approach involves using a unique quail xenograft assay that can be performed in standard labs, reducing the need for extensive animal testing and associated costs. This innovative method could significantly shorten the timeline and expenses involved in bringing new cancer therapies to patients.

Why it matters

Potential benefit: If successful, this research could lead to faster and more cost-effective development of new therapies for rare cancers, ultimately improving patient outcomes.

How similar studies have gone: Other research has shown promise in using innovative testing methods to accelerate drug development, suggesting that this approach could also be successful.

Where this research is happening

  • Teo Therapeutics Incorporated
    Beaverton, United States
    Active

Researchers

  • Principal investigator: Keller, Charles — Teo Therapeutics Incorporated
  • Study coordinator: Keller, Charles

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.