Improving drug delivery through microneedles in skin treatment
Official title: A translational approach to predicting small molecule drug permeation through microneedle-treated skin
Funded at University of Iowa · NIH-10925154 · Data updated 2026-11-12
This study is looking at how tiny microneedles can help deliver medications through the skin more effectively, making it easier for patients to get the treatment they need.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | September 10, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $399,104 |
| NIH project number | 5R35GM149337-02 |
| Project ID | NIH-10925154 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals requiring medication that is difficult to deliver through traditional methods, such as those with chronic conditions.
✕Less likely to help
Patients who do not require medication or those with conditions that can be effectively treated with existing delivery methods may not benefit from this research.
What this research studies
This research investigates how microneedles can enhance the delivery of small molecule drugs through the skin. By creating tiny pores in the skin, microneedles allow medications that typically struggle to penetrate the skin barrier to be absorbed more effectively. The study will explore various factors that influence drug absorption, both in laboratory settings and in living organisms, to optimize treatment options for patients. The ultimate goal is to develop new microneedle-based drug formulations that can improve health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective and convenient drug delivery methods for patients, reducing the need for injections or oral medications.
How similar studies have gone: Previous research has shown promise in using microneedles for drug delivery, indicating that this approach has potential for success.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Brogden, Nicole K — University of Iowa
- Study coordinator: Brogden, Nicole K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.