Improving DNA sequencing technology for better biomedical research
Realizing the potential of long-read sequencing technology
This study is working on making DNA sequencing easier and better, so more labs can use it to understand how genes work in humans and mice, especially helping those with less funding to join in on important research.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Santa Cruz NIH-funded |
| Lab location | 1 site (Santa Cruz, United States) |
| Project ID | NIH-10842983 on NIH RePORTER |
What this research studies
This research focuses on enhancing long-read sequencing technologies, such as those from Pacific Biosciences and Oxford Nanopore, to improve their usability and capabilities compared to short-read sequencing. The project aims to generate detailed transcriptomes for human and mouse tissues, which will provide crucial information for understanding gene expression. Additionally, the research will develop a user-friendly sequencing method that allows more laboratories, especially those with limited funding, to access high-quality DNA sequencing. This democratization of technology could significantly expand the genomics workforce and enhance research diversity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require detailed genomic analysis for better understanding and treatment.
Not a fit: Patients who do not require genomic analysis or whose conditions are not related to genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and comprehensive genomic analyses, benefiting a wide range of biomedical studies.
How similar studies have performed: Previous research has shown promise in enhancing sequencing technologies, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
Santa Cruz, United States
- University of California Santa Cruz — Santa Cruz, United States (Active)
Researchers
- Principal investigator: Vollmers, Christopher — University of California Santa Cruz
- Study coordinator: Vollmers, Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.