Improving diagnosis of peripheral artery disease in patients with chronic kidney disease
Establishing A New Diagnostic Paradigm for Peripheral Artery Disease among Patients with Chronic Kidney Disease
This study is looking to improve how we diagnose peripheral artery disease (PAD) in people who also have chronic kidney disease (CKD), by testing new ways to measure blood flow that might work better for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-10677577 on NIH RePORTER |
What this research studies
This research aims to develop a new diagnostic approach for peripheral artery disease (PAD) specifically in patients who have chronic kidney disease (CKD). It investigates how traditional diagnostic methods may not accurately identify PAD in CKD patients due to unique vascular conditions such as arterial stiffness. The study will evaluate the effectiveness of new cut-off points for diagnostic tests like the ankle-brachial index (ABI) and toe-brachial index (TBI) to better detect PAD in this population. By analyzing various cardiovascular risk factors, the research seeks to enhance the accuracy of PAD diagnosis among CKD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with chronic kidney disease who may also be at risk for peripheral artery disease.
Not a fit: Patients without chronic kidney disease or those who do not have risk factors for peripheral artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses of peripheral artery disease in patients with chronic kidney disease, potentially improving their treatment outcomes.
How similar studies have performed: Previous studies have indicated that traditional diagnostic criteria may not be effective for CKD patients, suggesting that this research could fill a critical gap in understanding PAD in this population.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Chen, Jing — Tulane University of Louisiana
- Study coordinator: Chen, Jing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.