Improving diagnosis of lymph node swelling in HIV patients in Malawi
Official title: Innovations in diagnosis for lymphadenopathy across HIV Centers of Excellence in Malawi
Funded at Univ of North Carolina Chapel Hill · NIH-10915169 · Data updated 2026-11-12
This study is looking at how to better diagnose swollen lymph nodes in people with HIV in Malawi, so they don’t get wrongly treated for tuberculosis when they might have other serious conditions, helping to ensure they get the right care and stay healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $544,250 |
| NIH project number | 1DP1CA291150-01 |
| Project ID | NIH-10915169 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV in Malawi who present with swollen lymph nodes.
✕Less likely to help
Patients who do not have HIV or do not present with lymphadenopathy may not benefit from this research.
What this research studies
This research focuses on understanding and improving the diagnosis of lymphadenopathy, or swollen lymph nodes, in patients living with HIV in Malawi. Many of these patients are misdiagnosed and treated for tuberculosis, even when tests are negative, potentially missing serious conditions like lymphoproliferative disorders. The study aims to identify barriers to accurate diagnosis and develop innovative diagnostic technologies to ensure timely and effective treatment. By enhancing diagnostic capabilities, the research seeks to reduce preventable deaths among HIV patients.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of serious conditions in HIV patients, ultimately saving lives.
How similar studies have gone: Previous research has shown that improving diagnostic methods for lymphoproliferative disorders can significantly enhance patient outcomes, indicating a promising approach.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Painschab, Matthew Scott — Univ of North Carolina Chapel Hill
- Study coordinator: Painschab, Matthew Scott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.