NIH-funded research R21 grant

Improving diagnosis of airway narrowing in infants

Official title: Computer-Vision and Computational Fluid Dynamics Analysis Pipeline to Improve Diagnosis in Pediatric Subglottic Stenosis

Funded at Seattle Children's Hospital · NIH-11231823 · Data updated 2026-11-12

This study is looking at a breathing problem in babies called subglottic stenosis, and it's working on a new way to use advanced imaging technology to better understand how this condition affects their breathing, so doctors can make smarter treatment choices for these little ones.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSeattle Children's Hospital
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$233,250
NIH project number7R21HL172011-02
Project IDNIH-11231823 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are infants diagnosed with pediatric subglottic stenosis who require evaluation for treatment options.

Less likely to help

Patients with other types of airway issues or those who do not have subglottic stenosis may not benefit from this research.

What this research studies

This research focuses on pediatric subglottic stenosis (SGS), a condition where the airway narrows, making it difficult for infants to breathe. The project aims to develop a new analysis pipeline using computer vision and computational fluid dynamics to provide more accurate diagnoses and treatment plans. By utilizing advanced imaging techniques, the research seeks to quantify the severity of airway obstruction and its impact on breathing effort, which is currently not well understood. This improved diagnostic approach could lead to better treatment decisions and outcomes for affected infants.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatments for infants with airway narrowing, potentially reducing the need for invasive procedures.

How similar studies have gone: While the approach of using advanced imaging techniques for airway assessment is promising, it is relatively novel and has not been extensively tested in this specific context.

Where this research is happening

  • Seattle Children's Hospital
    Seattle, United States
    Active

Researchers

  • Principal investigator: Barbour, Michael — Seattle Children's Hospital
  • Study coordinator: Barbour, Michael

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.