Improving diagnosis and treatment of ovarian cancer
SPORE in Ovarian Cancer
This study is looking for better ways to detect and treat ovarian cancer early, helping patients by finding new methods to spot the disease and testing new treatments to improve their chances of recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10935404 on NIH RePORTER |
What this research studies
This research focuses on ovarian cancer, one of the most aggressive forms of cancer, aiming to reduce its incidence and mortality. The program translates laboratory discoveries into clinical applications through three main projects. These projects include developing a novel method to sample fallopian tubes and ovaries for early detection of cancerous lesions, and evaluating new combination therapies for advanced ovarian cancer. By identifying specific biomarkers and understanding treatment resistance, the research seeks to enhance clinical management and treatment outcomes for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include women diagnosed with ovarian cancer, particularly those with recurrent disease or specific genetic mutations like ARID1A.
Not a fit: Patients with non-ovarian cancers or those without the specific genetic markers targeted by this research may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and more effective treatments for ovarian cancer, significantly improving patient outcomes.
How similar studies have performed: Previous research has shown promise in similar approaches, particularly in identifying biomarkers and developing targeted therapies for ovarian cancer.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Shih, Ie-Ming — Johns Hopkins University
- Study coordinator: Shih, Ie-Ming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.