Improving diagnosis and care for familial hypercholesterolemia

Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH

NIH-funded research Geisinger Clinic · NIH-11043251

This study is working to make it easier for doctors to spot and treat familial hypercholesterolemia (FH), a genetic condition that causes high cholesterol and can lead to heart problems, so that both kids and adults can get the help they need earlier and stay healthier.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGeisinger Clinic NIH-funded
Lab location1 site (Danville, United States)
Project IDNIH-11043251 on NIH RePORTER

What this research studies

This research focuses on enhancing the diagnosis and treatment of familial hypercholesterolemia (FH), a genetic condition that leads to high cholesterol levels and increases the risk of heart disease. The project aims to implement a program within primary care settings that promotes early identification of FH in both children and adults. By utilizing patient and clinician insights, the research seeks to develop effective strategies for screening and treatment that are sustainable and applicable in various healthcare environments. The goal is to close the care gap that currently leads to late diagnoses and preventable cardiovascular issues.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with familial hypercholesterolemia, as well as children aged 9-11 and adults aged 40 and above who may be at risk.

Not a fit: Patients without familial hypercholesterolemia or those who do not fall within the targeted age groups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and better management of familial hypercholesterolemia, significantly reducing the risk of heart disease in affected individuals.

How similar studies have performed: Previous research has shown success in implementing similar screening programs for genetic disorders, indicating a promising approach for this project.

Where this research is happening

Danville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.