Improving diabetes care for adults with uncontrolled blood sugar

A Multiphase Optimization Strategy to Enhance Diabetes Management Interventions for Patients with Uncontrolled Diabetes

NIH-funded research University of Michigan at Ann Arbor · NIH-11195903

This project will try different support strategies to help adults with uncontrolled diabetes take their medicines regularly and lower their A1c.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11195903 on NIH RePORTER

What this research studies

You'll be invited to join a program run by University of Michigan researchers working with a pharmacy chain and local partners. The team will randomly assign participants to different combinations of support components (for example, medication counseling, help with food or other social needs, and tools to address beliefs about medicines) to see which mix works best. They will collect survey and health data, interview some participants for feedback, and analyze costs to find approaches that are both effective and affordable. The goal is to pick a practical package of supports that can be scaled up to help more people manage diabetes.

Who could benefit from this research

Good fit: Adults (age 21 and older) with uncontrolled diabetes who have trouble taking diabetes medicines or face social barriers like food insecurity are the ideal candidates.

Not a fit: People with well-controlled diabetes, children, or those whose needs are strictly medical (not related to medication adherence or social support) are unlikely to benefit directly from participation.

Why it matters

Potential benefit: If successful, this work could help people with uncontrolled diabetes stick to their medications and lower their HbA1c, which may reduce complications.

How similar studies have performed: Previous multi-component adherence programs have sometimes improved medication-taking and A1c, but results are mixed and using a multiphase optimization strategy to systematically find the best combination is a newer approach.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Complications of Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.