Improving detection of second breast cancers in survivors with AI
Project 3
['FUNDING_P01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11182608
This project looks at whether AI and risk tools can help find second breast cancers earlier in people who survived breast cancer.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-11182608 on ClinicalTrials.gov |
What this research studies
You would be asked to share your mammograms and health records so researchers can build and test AI tools that predict who is most likely to have a second breast cancer missed between annual mammograms. The team will train the models on data from UC Davis and other sites and then test the models on separate groups to make sure they work across different populations. They will compare AI-enhanced reading of surveillance mammograms to usual care, examine whether performance differs by race, and study social factors that lead to missed cancers. Researchers will also ask doctors and survivors whether a risk-based screening approach would be acceptable.
Who could benefit from this research
Good fit: Ideal candidates are breast cancer survivors who get routine surveillance mammography and who are willing to share imaging and health records, including survivors from diverse racial and socioeconomic backgrounds.
Not a fit: People without a prior breast cancer history or those not undergoing surveillance mammography would not directly benefit from this project.
Why it matters
Potential benefit: If successful, this work could help detect second breast cancers earlier, reduce missed cancers, and support more personalized surveillance for survivors.
How similar studies have performed: AI has improved mammogram detection in other populations, but applying and externally validating these approaches specifically for survivors and across racial groups is less well established.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, JANIE M — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: LEE, JANIE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer