Improving detection of disease markers in tiny vesicles from body fluids
Development of plasmon-enhanced biosensing for multiplexed profiling of extracellular vesicles
This study is working on a new way to look at tiny particles released by your cells that can help doctors find diseases more accurately using simple tests, making it easier for everyone to get the information they need about their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10906865 on NIH RePORTER |
What this research studies
This research focuses on developing a new technology to analyze extracellular vesicles (EVs), which are tiny particles released by cells and found in various body fluids. These vesicles carry important biological information, such as proteins and genetic material, that can help in diagnosing diseases. The project aims to create a platform that allows for the simultaneous analysis of multiple markers within individual EVs, overcoming current limitations in sensitivity and efficiency. By utilizing advanced nanoplasmonic sensing techniques, the researchers hope to enhance the accuracy of disease detection from non-invasive samples.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions that can be diagnosed through the analysis of extracellular vesicles, such as cancers or cardiovascular diseases.
Not a fit: Patients who do not have conditions detectable through extracellular vesicle analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and less invasive diagnostic methods for various diseases.
How similar studies have performed: Previous research has shown promise in using nanoplasmonic techniques for detecting disease-specific extracellular vesicles, indicating a potential for success in this novel approach.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Im, Hyungsoon — Massachusetts General Hospital
- Study coordinator: Im, Hyungsoon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.