Improving detection of biomolecules using electrochemical methods.
Developing a redox-mediated single NP detection for bioconjugate analysis.
['FUNDING_R21'] · UNIVERSITY OF NEVADA RENO · NIH-10952012
This study is exploring a new way to quickly and accurately detect important proteins in the body, like antibodies and antigens, which could help improve tests for various health conditions.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEVADA RENO (nih funded) |
| Locations | 1 site (RENO, UNITED STATES) |
| Trial ID | NIH-10952012 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the detection of biomolecules, specifically antibodies and antigens, through a novel electrochemical approach. By utilizing single-entity electrochemistry, the study aims to achieve rapid and precise analysis of individual bioconjugates, which are molecules formed by the binding of an antibody to an antigen. The methodology involves tagging antibodies with gold nanoparticles and measuring the electrochemical reactions at ultramicroelectrodes to detect these interactions. This could lead to more efficient diagnostic tools in biomedical research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring precise biomarker detection for conditions that involve antibody-antigen interactions.
Not a fit: Patients with conditions that do not involve antibody or antigen detection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with faster and more accurate diagnostic tests for various diseases.
How similar studies have performed: Other research has shown promise in using electrochemical methods for biomolecule detection, indicating potential success for this approach.
Where this research is happening
RENO, UNITED STATES
- UNIVERSITY OF NEVADA RENO — RENO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALPUCHE-AVILES, MARIO ALBERTO — UNIVERSITY OF NEVADA RENO
- Study coordinator: ALPUCHE-AVILES, MARIO ALBERTO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.