Improving detection and risk assessment for Barrett's esophagus
Official title: Academic-Industrial Partnership for Barrett's Esophagus Detection and Risk Assessment
Funded at Johns Hopkins University · NIH-11038033 · Data updated 2026-11-12
This study is looking for ways to better understand and predict the risk of cancer in people with Barrett's esophagus, a condition caused by long-term acid reflux, so that doctors can provide more accurate check-ups and help keep patients healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $752,603 |
| NIH project number | 5R01CA287294-07 |
| Project ID | NIH-11038033 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Barrett's esophagus, particularly those with a history of gastroesophageal reflux disease (GERD).
✕Less likely to help
Patients without Barrett's esophagus or those who do not have a history of GERD may not benefit from this research.
What this research studies
This research focuses on Barrett's esophagus, a condition that can lead to esophageal cancer due to chronic acid reflux. It aims to enhance the methods used to assess the risk of cancer in patients with Barrett's esophagus by developing new biomarkers and algorithms. The study will continue a successful partnership between academia and industry to create better diagnostic tools and improve patient outcomes. Patients will be monitored and assessed to determine their risk of progression to cancer more accurately.
Why it matters
Potential benefit: If successful, this research could lead to more accurate risk assessments for patients with Barrett's esophagus, potentially improving early detection and treatment of esophageal cancer.
How similar studies have gone: Previous research has shown promise in developing biomarkers for cancer risk assessment in Barrett's esophagus, indicating that this approach has potential for success.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Meltzer, Stephen J — Johns Hopkins University
- Study coordinator: Meltzer, Stephen J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.