Improving dental materials to prevent tooth decay around fillings
Microenvironmental characterization and manipulation to prevent secondary caries
This study is looking at new types of dental materials that can help keep your teeth healthy by preventing new cavities from forming around fillings, making them last longer and work better for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project ID | NIH-10802985 on NIH RePORTER |
What this research studies
This research focuses on developing new dental composite materials that can help prevent the recurrence of tooth decay, known as secondary caries, around existing dental restorations. By manipulating the microbial environment in the mouth, the study aims to create materials that release beneficial ions like magnesium and zinc, which can promote a healthier oral microbiome. The research involves optimizing these materials to ensure they effectively maintain a healthy pH level around dental fillings, thus reducing the risk of further decay. Patients may benefit from longer-lasting dental restorations that are less prone to failure due to caries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with existing dental restorations who are at risk for secondary caries.
Not a fit: Patients without dental restorations or those who do not have a history of dental caries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to dental materials that significantly reduce the incidence of secondary caries, improving oral health and reducing the need for repeat dental procedures.
How similar studies have performed: Previous research has shown promise in using bioactive materials to alter the oral microbiome, suggesting that this approach may be effective.
Where this research is happening
Corvallis, United States
- Oregon State University — Corvallis, United States (Active)
Researchers
- Principal investigator: Koley, Dipankar — Oregon State University
- Study coordinator: Koley, Dipankar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.