Improving dengue virus tracking to understand its genetic diversity
Enhancing dengue virus genomic surveillance to uncover circulating genetic diversity
This study is working to improve how we track and understand dengue viruses in the Caribbean by creating a new way to look at their genetic makeup and using travel data to help keep everyone safe from outbreaks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10471494 on NIH RePORTER |
What this research studies
This research aims to enhance the genomic surveillance of dengue virus, which is crucial for public health measures. By developing a universal whole genome sequencing method and forming a collaborative network in the Caribbean, the project seeks to uncover the genetic diversity of circulating dengue viruses. It will also utilize travel surveillance data to inform broader genomic surveillance efforts and create a new classification system for dengue virus variants. This comprehensive approach aims to modernize how we monitor and respond to dengue outbreaks.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in or traveling to regions affected by dengue virus, particularly in the Caribbean.
Not a fit: Patients who do not reside in or travel to dengue-affected areas may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective public health strategies to control and prevent dengue outbreaks.
How similar studies have performed: Other research has successfully utilized genomic surveillance for pathogens like SARS-CoV-2, indicating potential for similar success with dengue virus.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Grubaugh, Nathan Dale — Yale University
- Study coordinator: Grubaugh, Nathan Dale
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.