Improving dementia understanding for Latino communities in Latin America and the United States
Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat2)
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11480850
This project brings together partners across Latin America and the US to learn how Alzheimer's disease and frontotemporal dementia affect Latino people by collecting clinical, brain imaging, genetic, and social health data.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11480850 on ClinicalTrials.gov |
What this research studies
You're invited to join a large consortium that is enrolling thousands of people—including those with Alzheimer's, frontotemporal dementia, and healthy volunteers—across Argentina, Brazil, Chile, Colombia, Mexico, Peru, and the United States. Doctors and researchers will collect medical exams, memory tests, brain scans, and whole-genome sequencing alongside information about education, income, and neighborhood to see how social and genetic factors shape dementia. They will combine 3,000 new participants with existing ReDLat datasets and related NIH-funded data to build models tailored to Latino populations and compare findings with US participants. Study teams aim to improve diagnosis and make future treatments and clinical trials more relevant for Latino communities.
Who could benefit from this research
Good fit: Ideal participants are Latino adults with Alzheimer's disease or frontotemporal dementia, family members from large pedigrees for genetic study, and healthy Latino controls willing to provide medical, imaging, and genetic information.
Not a fit: People without Latino heritage, those with unrelated neurological conditions, or individuals unable to travel to participating sites or consent to imaging and genetic testing may not be eligible or benefit.
Why it matters
Potential benefit: If successful, this work could lead to more accurate diagnosis, better-tailored treatments, and more inclusive clinical trials for Latino people with dementia.
How similar studies have performed: Earlier ReDLat work and other international dementia consortia have identified population-specific genetic and imaging patterns, and this larger multimodal, multi-country effort builds on and expands that approach.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MILLER, BRUCE L — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: MILLER, BRUCE L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.