Improving deep tissue imaging using advanced optical techniques

Overcoming the Multiple Scattering Limit in Optical Coherence Tomography

NIH-funded research Cornell University · NIH-11128482

This study is working on improving a special imaging technique called optical coherence tomography (OCT) to help doctors see deeper layers of tissue more clearly, which can lead to better diagnoses and monitoring for patients with various medical conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCornell University NIH-funded
Lab location1 site (Ithaca, United States)
Project IDNIH-11128482 on NIH RePORTER

What this research studies

This research focuses on enhancing the capabilities of optical coherence tomography (OCT) to visualize deeper layers of tissue, which is crucial for diagnosing and monitoring various medical conditions. By addressing the challenges posed by optical scattering in dense tissues, the project aims to develop innovative methods that allow for clearer and more detailed imaging. The approach involves using longer wavelengths of light and advanced imaging configurations to significantly improve the depth and quality of the images obtained. Patients may benefit from more accurate diagnoses and better monitoring of their conditions through improved imaging techniques.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals requiring detailed imaging of dense tissues, such as those with neurological or cutaneous conditions.

Not a fit: Patients with conditions that do not require deep tissue imaging or those who are not undergoing any imaging procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective diagnostic tools for a variety of medical conditions by enabling deeper and clearer imaging of tissues.

How similar studies have performed: Other research in optical imaging has shown promising results in enhancing imaging depth and quality, indicating that this approach has potential for success.

Where this research is happening

Ithaca, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.