Improving deep brain stimulation for Parkinson's disease using biomarkers
An Integrated Biomarker Approach to Personalized, Adaptive Deep Brain Stimulation in Parkinson Disease
['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-11019683
This study is looking at a new way to make deep brain stimulation for Parkinson's disease even better by using real-time signals from your body to automatically adjust the treatment, which could help reduce symptoms like tremors and stiffness for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11019683 on ClinicalTrials.gov |
What this research studies
This research investigates how to enhance deep brain stimulation (DBS) therapy for Parkinson's disease by using physiological biomarkers to adjust stimulation parameters automatically. The approach aims to personalize treatment by recording signals related to motor symptoms and dynamically adjusting the stimulation in real-time. By integrating multiple biomarkers, the study seeks to optimize DBS therapy over various time scales, potentially leading to better management of symptoms like tremors and rigidity. Patients may experience improved outcomes through this innovative method of treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are considering or currently undergoing deep brain stimulation therapy.
Not a fit: Patients who do not have Parkinson's disease or those who are not candidates for deep brain stimulation therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using adaptive DBS techniques, indicating potential for success with this integrated biomarker approach.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TURNER, DENNIS ALAN — DUKE UNIVERSITY
- Study coordinator: TURNER, DENNIS ALAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.