Improving deep brain stimulation for Parkinson's disease using advanced imaging techniques
An Application of Advanced Imaging and Visualization to Clinical Deep Brain Stimulation
['FUNDING_R37'] · DUKE UNIVERSITY · NIH-11264350
This study is looking to make deep brain stimulation for Parkinson's disease even better by using new imaging technology to help doctors find the right spot in the brain during surgery, which could lead to improved results for patients.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11264350 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the effectiveness of deep brain stimulation (DBS) for Parkinson's disease by utilizing advanced imaging and visualization technologies. It aims to improve the surgical targeting of the subthalamic nucleus (STN) through innovative MRI techniques and patient-specific modeling. By employing Magnetic Resonance Fingerprinting (MRF), the project seeks to create detailed 3D maps of brain structures, which will help in accurately identifying the STN during surgery. This approach could lead to better outcomes for patients undergoing DBS by optimizing the precision of the procedure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are considering or are candidates for deep brain stimulation therapy.
Not a fit: Patients who do not have Parkinson's disease or those who are not candidates for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve motor symptoms and quality of life for patients with Parkinson's disease receiving deep brain stimulation.
How similar studies have performed: Previous research has shown promising results using advanced imaging techniques in similar contexts, indicating potential for success in this novel application.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCINTYRE, CAMERON — DUKE UNIVERSITY
- Study coordinator: MCINTYRE, CAMERON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.