Improving deep brain stimulation for Parkinson's disease

Optimizing coordinated reset deep brain stimulation for Parkinson's disease

NIH-funded research University of Minnesota · NIH-10869897

This study is exploring a new way to use deep brain stimulation to help people with Parkinson's disease feel better and move more easily, while also trying to reduce side effects.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-10869897 on NIH RePORTER

What this research studies

This research investigates a new method of deep brain stimulation (DBS) called coordinated reset (CR) DBS, which aims to enhance treatment for Parkinson's disease. By using a unique burst pattern of lower intensity stimulation, the study seeks to minimize side effects and improve motor function in patients. The research will optimize the stimulation parameters and compare the effects of CR DBS on different brain regions. Patients will be monitored to assess the long-term benefits of this innovative approach.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are considering or currently undergoing deep brain stimulation therapy.

Not a fit: Patients with Parkinson's disease who are not candidates for deep brain stimulation or those with early-stage disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for patients with Parkinson's disease.

How similar studies have performed: Previous studies have shown promising results with coordinated reset deep brain stimulation, indicating potential for significant advancements in treatment.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.