Improving deep brain stimulation for motor diseases
Cerebellar Deep Brain Stimulation
This study is looking at how deep brain stimulation can help people with severe movement disorders by focusing on a part of the brain that controls coordination, using mice to learn more about the brain's signals, so we can create better treatments for those who don’t get better with regular medications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10909216 on NIH RePORTER |
What this research studies
This research investigates the use of deep brain stimulation (DBS) to treat severe motor diseases by targeting specific areas in the cerebellum, a brain region crucial for movement and coordination. The study employs a genetic toolkit in mice to create models that mimic motor diseases, allowing researchers to identify unique neural signatures associated with these conditions. By understanding these signatures, the research aims to develop more effective DBS techniques that could provide targeted treatment for patients who do not respond to traditional medications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from severe motor diseases who have not found relief through conventional medications.
Not a fit: Patients with mild motor impairments or those whose conditions are well-managed with existing treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with severe motor diseases, enhancing their quality of life.
How similar studies have performed: Previous research has shown promise in using deep brain stimulation for various neurological conditions, suggesting that this approach could yield significant advancements.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Sillitoe, Roy Vincent — Baylor College of Medicine
- Study coordinator: Sillitoe, Roy Vincent
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.