NIH-funded research R01 grant

Improving decision-making for pulmonary arterial hypertension treatment

Official title: PHORA-Pulmonary Hypertension Outcome Risk Assessment

Funded at Icahn School of Medicine at Mount Sinai · NIH-10928758 · Data updated 2026-11-12

This study is creating a helpful tool called PHORA that will guide doctors in choosing the best treatments for people, both adults and kids, with pulmonary arterial hypertension (PAH), making it easier for them to get the care they need.

More Pulmonary Hypertension research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startJanuary 5, 2024
Project endJune 30, 2027
Funding year2024
Award (this year)$607,038
NIH project number5R01HL164906-04
Project IDNIH-10928758 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include both adults and children diagnosed with pulmonary arterial hypertension.

Less likely to help

Patients with other forms of pulmonary hypertension that do not fall under the PAH category may not benefit from this research.

What this research studies

This research aims to develop a clinical decision support system called PHORA, which will assist healthcare providers in making informed treatment decisions for patients with pulmonary arterial hypertension (PAH). By analyzing data from various clinical trials and registries, the system will provide tailored recommendations for both adults and children. The project involves collaboration among experts in multiple fields, including biomedical engineering and computer science, to ensure the system is user-friendly and effective. Ultimately, the goal is to enhance patient outcomes and streamline clinical trial designs.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with pulmonary arterial hypertension.

How similar studies have gone: Previous research has shown promise in using clinical decision support systems to improve treatment outcomes in various medical fields, indicating potential success for this approach in PAH.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Benza, Raymond Louis — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Benza, Raymond Louis

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.