Improving data collection for cryo-electron microscopy
Automated, optimized, intelligent data collection for cryo-EM
['FUNDING_R01'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-10878905
This study is working on smarter software to help scientists take better and faster pictures of tiny biological structures, which could lead to new treatments for diseases like COVID-19, ultimately benefiting patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10878905 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the automation and optimization of data collection in cryo-electron microscopy (cryo-EM), a technique crucial for visualizing the structures of important biological molecules. By developing intelligent software that can efficiently manage the acquisition of thousands of images, the project aims to improve the quality and speed of data collection. This advancement could lead to better understanding of diseases, including COVID-19, by providing clearer molecular images. Patients may benefit indirectly through improved research outcomes and potential new treatments derived from these insights.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals affected by diseases that require advanced molecular understanding, such as COVID-19.
Not a fit: Patients with conditions unrelated to molecular biology or those not involved in research studies may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate identification of molecular structures, potentially accelerating the development of new therapies for diseases like COVID-19.
How similar studies have performed: Previous research in cryo-EM has shown significant success in improving our understanding of biological systems, indicating that advancements in automation could further enhance these outcomes.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LANDER, GABRIEL C — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: LANDER, GABRIEL C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.