Improving cryopreservation of Xenopus sperm for accessible transgenic research
Official title: Applied Research
Funded at Marine Biological Laboratory · NIH-11393866 · Data updated 2026-11-12
This grant supports the National Xenopus Resource to improve storing Xenopus sperm so researchers can reliably create transgenic embryos.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Marine Biological Laboratory NIH-funded |
| Lab location | 1 site (Woods Hole, United States) |
| Project start | August 12, 2010 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $53,129 |
| NIH project number | 5P40OD010997-17 |
| Project ID | NIH-11393866 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable in the traditional patient sense; the grant serves researchers and their ability to study Xenopus biology and related human disease models.
✕Less likely to help
Direct patient benefit is not the focus of this grant; it supports researchers and laboratories.
What this research studies
If funded, this project will continue developing and refining methods to cryopreserve Xenopus sperm, making it easier for labs to maintain diverse strains without keeping live colonies. The team will explore enhancements to current freezing techniques and test a new packaging approach using French straws to increase efficiency and reduce space needs. By improving reliability, more researchers can access high-quality genetic materials to advance their work. The effort takes place at the Marine Biological Laboratory in Woods Hole, serving the wider Xenopus research community.
Why it matters
Potential benefit: Researchers will have easier, more reliable access to preserved sperm, speeding up genetic and developmental studies.
How similar studies have gone: Cryopreservation improvements have shown promise in enabling broader use of genetic resources, though challenges with reliability remain.
Where this research is happening
-
Marine Biological Laboratory
Woods Hole, United States Active
Researchers
- Principal investigator: Horb, Marko E — Marine Biological Laboratory
- Study coordinator: Horb, Marko E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.