Improving CPR techniques to reduce brain injury after cardiac arrest
Goal directed cardiopulmonary resuscitation in cardiac arrest using a novel physiological target: A pilot mechanistic randomized control trial
This study is looking at new ways to make CPR better during a heart emergency by using special tools to check how well oxygen is getting to the brain and how much carbon dioxide is in the body, with the hope of helping patients recover more fully after their heart starts beating again.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10887520 on NIH RePORTER |
What this research studies
This research investigates new methods to enhance cardiopulmonary resuscitation (CPR) during cardiac arrest, focusing on real-time monitoring of carbon dioxide levels and brain oxygenation. By using advanced technologies, the study aims to improve the quality of CPR, which is crucial for minimizing brain damage caused by lack of oxygen. The approach involves a multi-site trial where patients experiencing cardiac arrest will receive CPR guided by physiological feedback, potentially leading to better outcomes. The goal is to understand how these techniques can reduce secondary injuries that occur after the heart is restarted.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who suffer from cardiac arrest and are receiving CPR in a hospital setting.
Not a fit: Patients who have pre-existing severe brain injuries or those who do not experience cardiac arrest may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve survival rates and reduce brain injuries in patients who experience cardiac arrest.
How similar studies have performed: Previous studies have shown promise in using physiological feedback during CPR, indicating that this approach could lead to meaningful advancements in resuscitation techniques.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Parnia, Sam — New York University School of Medicine
- Study coordinator: Parnia, Sam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.