Improving control of prosthetic limbs for amputees using advanced neural interfaces

Regenerative Ultramicroelectrode arrays for sensory-motor specific interfacing

NIH-funded research University of Arizona · NIH-11078035

This study is working on making prosthetic limbs feel and move more naturally for amputees by creating special technology that helps the devices better understand signals from the nervous system, so users can have a smoother experience with their artificial limbs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona NIH-funded
Lab location1 site (Tucson, United States)
Project IDNIH-11078035 on NIH RePORTER

What this research studies

This research focuses on enhancing the functionality of prosthetic limbs for amputees by developing advanced neural interfaces that can better interpret sensory feedback. The project aims to create a regenerative ultramicroelectrode array that allows for more precise communication between the nervous system and prosthetic devices. By utilizing innovative techniques to improve the selectivity of neural recordings and stimulation, the research seeks to reduce common issues such as signal deterioration and sensory artifacts. This approach could lead to more intuitive control of prosthetics, allowing users to experience a more natural interaction with their artificial limbs.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who have experienced upper limb amputations and are seeking improved prosthetic solutions.

Not a fit: Patients with lower limb amputations or those who do not use prosthetic devices may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the quality of life for amputees by providing them with more effective and responsive prosthetic limbs.

How similar studies have performed: Previous research has shown promise in using advanced neural interfaces for prosthetic control, indicating that this approach could lead to significant advancements in the field.

Where this research is happening

Tucson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.