Improving communication in Parkinson's disease through new therapies
Preclinical trial for dysarthria treatment in Parkinson disease
This study is looking at how different therapies, like exercise and social activities, can help improve communication and emotional health for people with Parkinson's disease by focusing on a brain chemical called norepinephrine, using a rat model to find better treatments for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10989872 on NIH RePORTER |
What this research studies
This research investigates how different therapies can enhance communication, cognition, and emotional well-being in individuals with Parkinson's disease. It focuses on modulating norepinephrine levels through exercise, medication, and social interactions to address communication deficits caused by the disease. The study uses a rat model that closely mimics human Parkinson's disease to explore the effectiveness of these approaches and their potential side effects. By understanding the underlying neural mechanisms, the research aims to develop better treatment options for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience communication difficulties.
Not a fit: Patients with Parkinson's disease who do not have communication deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved communication abilities and overall quality of life for patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using similar approaches to improve communication and cognitive functions in patients with neurological disorders.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Ciucci, Michelle Renee — University of Wisconsin-Madison
- Study coordinator: Ciucci, Michelle Renee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.