Improving colorectal cancer screening outcomes for diverse communities
Official title: Addressing Disparities in Outcomes of Screening for Colorectal Cancer in Community-Based Settings
Funded at Ohio State University · NIH-11082336 · Data updated 2026-11-12
This study is looking at how well colorectal cancer screenings work for Black and Native American communities, aiming to find ways to improve the screening process and follow-up care so everyone gets the help they need.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | May 4, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $604,360 |
| NIH project number | 5R01CA278052-03 |
| Project ID | NIH-11082336 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals aged 85 and older, particularly those from Black and Native American communities.
✕Less likely to help
Patients who are not part of the targeted age group or racial/ethnic communities may not receive direct benefits from this research.
What this research studies
This research investigates the disparities in colorectal cancer screening outcomes, particularly focusing on Black and Native American populations. It aims to evaluate the entire screening process, from the quality of tests to the follow-up care received after abnormal results. By analyzing data from approximately 3.8 million individuals over nearly two decades, the study seeks to identify effective strategies to enhance health equity in cancer screening. The approach combines quantitative data analysis with qualitative insights to understand barriers and facilitators in the screening continuum.
Why it matters
Potential benefit: If successful, this research could lead to improved colorectal cancer screening and treatment outcomes for underserved populations.
How similar studies have gone: Previous research has shown that targeted interventions can effectively reduce disparities in cancer screening, indicating a promising avenue for this study.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Doubeni, Chyke Abadama — Ohio State University
- Study coordinator: Doubeni, Chyke Abadama
Related research
Other NIH-funded projects on the same topics.
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Improving colorectal cancer screening and follow-up care.
This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.
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Colorectal cancer prognosis through a broad, collaborative study
A large, multi-center study follows people newly diagnosed with colorectal cancer to find biomarkers and patterns that predict outcomes and guide future care.
-
Ceramides and how they affect metabolism and colorectal cancer in adults
A study in adults with obesity-related health issues will explore how a fat-related molecule called ceramide influences metabolic problems and colorectal cancer risk.
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Automated point-of-care DNA methylation test for colorectal cancer in LMICs
A fast, affordable blood test using DNA markers to help identify people at higher risk of colorectal cancer in low- and middle-income countries.
-
Rewiring Colorectal Cancer to Harness Therapeutic Hyperactivation
A Yale team is exploring brain-storming new ways to treat colorectal cancer by safely boosting certain cancer signaling pathways to kill cancer cells and by reshaping cancer cell states to improve responses to existing therapies.
-
Comparative modeling to guide colorectal cancer screening and care
A researcher team will use computer models to study how access to care, risk, and new screening options affect colorectal cancer outcomes and costs for adults in the US.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.