NIH-funded research R01 grant

Improving colorectal cancer screening in Appalachia through mailed tests

Official title: Strategies for Optimizing a Mailed FIT Program in Appalachia

Funded at Ohio State University · NIH-10931408 · Data updated 2026-11-12

This study is all about making it easier for people in the Appalachian region to get screened for colorectal cancer by sending a simple test they can do at home, and it aims to find out how to help more folks complete and return their tests so they can stay healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startAugust 28, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$468,291
NIH project number5R01CA282162-02
Project IDNIH-10931408 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 45-75 living in the Appalachian region who are at average risk for colorectal cancer.

Less likely to help

Patients outside the age range of 45-75 or those with a higher risk for colorectal cancer may not benefit from this research.

What this research studies

This research focuses on enhancing colorectal cancer screening rates in the Appalachian region by implementing a mailed fecal immunochemical test (FIT) program. The FIT test can be completed at home, making it more accessible for individuals who may face barriers to traditional screening methods. The study aims to identify and address common obstacles that prevent participants from returning completed tests, thereby increasing participation in screening programs. By collaborating with local health centers in areas with high colorectal cancer rates, the research seeks to develop effective strategies to improve health outcomes in these communities.

Why it matters

Potential benefit: If successful, this research could significantly increase colorectal cancer screening rates, leading to earlier detection and better outcomes for patients.

How similar studies have gone: Previous research has shown that mailed FIT programs can increase colorectal cancer screening rates, indicating that this approach has potential for success.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Reiter, Paul L — Ohio State University
  • Study coordinator: Reiter, Paul L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.