Improving colorectal cancer screening for people with Lynch syndrome

Optimal Colorectal Cancer Surveillance Strategy for Lynch Syndrome by Genotype

NIH-funded research Columbia University Health Sciences · NIH-11047374

This study is looking at how to improve cancer check-ups for people with Lynch syndrome, a genetic condition that raises the risk of colorectal cancer, so they can catch it early and have better outcomes, especially focusing on making sure everyone, including Black individuals who are diagnosed younger, gets the screenings they need.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11047374 on NIH RePORTER

What this research studies

This research focuses on enhancing colorectal cancer surveillance strategies specifically for individuals with Lynch syndrome, a genetic condition that increases cancer risk. By analyzing genetic factors and tailoring screening approaches, the study aims to identify the most effective methods for early detection of colorectal cancer. The goal is to improve patient outcomes by ensuring that those at higher risk receive appropriate and timely screenings, ultimately leading to better survival rates. The research also addresses disparities in screening adherence among different populations, particularly Black individuals who are often diagnosed at younger ages.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Lynch syndrome who are at increased risk for early-onset colorectal cancer.

Not a fit: Patients without Lynch syndrome or those who do not have a family history of colorectal cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized colorectal cancer screening strategies, significantly improving early detection and survival rates for at-risk patients.

How similar studies have performed: Previous research has shown that tailored screening approaches can improve adherence and outcomes in cancer prevention, suggesting that this study builds on established successful strategies.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer EtiologyCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.