Improving colorectal cancer screening for people with Lynch Syndrome
Optimal Colorectal Cancer Surveillance Strategy for Lynch Syndrome by Genotype
This study is looking to improve colorectal cancer screening for people with Lynch Syndrome by creating personalized recommendations based on their unique genetic makeup, so they can get the right care without unnecessary procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10894888 on NIH RePORTER |
What this research studies
This research aims to enhance colorectal cancer (CRC) screening strategies specifically for individuals with Lynch Syndrome, a genetic condition that significantly increases the risk of developing CRC. The study will investigate how to tailor screening recommendations based on the specific genetic profile of each patient, rather than applying a uniform approach. By analyzing the varying risks associated with different genotypes, the research seeks to reduce unnecessary procedures and improve the quality of life for patients. The findings could lead to more personalized and effective surveillance strategies that align with individual risk levels.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Lynch Syndrome who are at high risk for colorectal cancer.
Not a fit: Patients without Lynch Syndrome or those at average risk for colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized colorectal cancer screening, reducing unnecessary procedures and improving patient quality of life.
How similar studies have performed: Previous research has shown that personalized screening approaches can improve outcomes in other hereditary cancer syndromes, suggesting potential success for this tailored strategy.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Hur, Chin — Columbia University Health Sciences
- Study coordinator: Hur, Chin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.