Improving colorectal cancer prevention through personalized screening and genetic data.

Personalized Colorectal Cancer Prevention: Integrating Individual Screening and Follow Up Information with Genetic Data

['FUNDING_OTHER'] · DURHAM VA MEDICAL CENTER · NIH-10925426

This study is looking to improve how we prevent colorectal cancer by combining personal screening history with genetic information, so we can better identify who needs more frequent check-ups and who can wait, making sure everyone gets the right care at the right time.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorDURHAM VA MEDICAL CENTER (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-10925426 on ClinicalTrials.gov

What this research studies

This research aims to enhance colorectal cancer (CRC) prevention by integrating individual screening and follow-up information with genetic data. It focuses on developing more precise risk stratification methods that consider both clinical and genetic factors, allowing for tailored screening approaches. By identifying individuals at higher risk for CRC, the study seeks to optimize the use of colonoscopy resources, ensuring timely and appropriate screening while minimizing unnecessary procedures for those at lower risk. The research will utilize extensive VA resources, including clinical repositories and genomic biobanks, to refine current risk-assessment algorithms.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a family history of colorectal cancer or other risk factors that may warrant earlier or more frequent screening.

Not a fit: Patients who are at low risk for colorectal cancer and do not have any relevant family history or genetic predispositions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized colorectal cancer prevention strategies, ultimately reducing the incidence of the disease.

How similar studies have performed: Previous research has shown promise in using genetic data to improve cancer screening strategies, indicating that this approach could be effective.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.