Improving cognitive skills in children and adolescents with sickle cell disease

A Pilot Study of an Enhanced Program to Promote Adherence to eHealth Cognitive Rehabilitation in Sickle Cell Disease

NIH-funded research Children's Research Institute · NIH-11042880

This study is testing a new program to help kids and teens with sickle cell disease improve their memory and thinking skills through fun online training, while also getting support from family and friends to make it easier and more enjoyable.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionChildren's Research Institute NIH-funded
Lab location1 site (Washington, United States)
Project IDNIH-11042880 on NIH RePORTER

What this research studies

This research aims to enhance cognitive rehabilitation for children and adolescents suffering from sickle cell disease (SCD) by evaluating a new program that promotes adherence to an eHealth working memory training called Cogmed. The program includes social support elements such as family kickoff events and peer navigator assistance to encourage participation and improve cognitive function. By focusing on working memory, which is often impaired in SCD patients, the study seeks to determine if these enhancements can lead to better engagement and outcomes. Participants will engage in home-based training designed to address cognitive deficits associated with their condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are children and adolescents diagnosed with sickle cell disease who may experience cognitive deficits.

Not a fit: Patients without a diagnosis of sickle cell disease or those who do not exhibit cognitive deficits may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve cognitive abilities and quality of life for children and adolescents with sickle cell disease.

How similar studies have performed: Previous studies have shown promise in using eHealth interventions for cognitive rehabilitation, suggesting potential for success in this novel approach.

Where this research is happening

Washington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.