Improving cognitive function using personalized brain stimulation techniques

Cognitive enhancement through model-based and individualized neurostimulation

NIH-funded research Washington University · NIH-10768735

This study is looking at how a special type of brain stimulation can help improve thinking and memory by using personalized brain models, so if you join, you'll get a treatment designed just for your brain to see if it can boost your mental performance.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10768735 on NIH RePORTER

What this research studies

This research investigates how transcranial electrical stimulation (tES) can enhance cognitive functions by using individualized brain models. By analyzing participants' brain activity through resting-state electroencephalography (EEG), the study aims to understand how tES affects brain dynamics and cognitive performance. The approach focuses on creating personalized neural models to optimize the stimulation process, addressing previous limitations in cognitive enhancement studies. Participants will receive tailored interventions based on their unique brain activity patterns to improve mental health outcomes.

Who could benefit from this research

Good fit: Ideal candidates are adults over 21 years old who may be experiencing cognitive challenges or mental health disorders.

Not a fit: Patients with severe neurological conditions or those who are not able to undergo noninvasive brain stimulation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for cognitive impairments and mental health disorders.

How similar studies have performed: Previous research has shown promise in using noninvasive brain stimulation techniques for cognitive enhancement, indicating potential success for this novel approach.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.