Improving cognitive function assessment in early Alzheimer's Disease using digital tools
DETECT-AD: Digital Evaluations and Technologies Enabling Clinical Translation for Alzheimer's Disease
This study is looking for older adults who are at risk for Alzheimer's Disease to try out a new way of checking how well their brain is working by using easy-to-use technology at home, which will help us understand their daily activities and how they might change over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10483176 on NIH RePORTER |
What this research studies
This research aims to enhance the evaluation of cognitive function in individuals at risk for Alzheimer's Disease (AD) through innovative, passive digital assessment methods conducted in the comfort of their homes. Participants will use a technology-agnostic platform that continuously collects data on mobility, cognition, sleep, and social engagement, generating digital biomarkers that reflect their everyday functioning. The study will simulate a clinical trial environment over 36 months, where participants will be categorized based on their amyloid status to assess the progression of cognitive decline. By utilizing remote assessments, the research seeks to provide a more accurate picture of cognitive health in older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are asymptomatic but at risk for Alzheimer's Disease, particularly those with defined amyloid status.
Not a fit: Patients who are already diagnosed with advanced Alzheimer's Disease or those without any cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of cognitive decline in Alzheimer's Disease, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in using digital tools for cognitive assessment, indicating that this approach could be effective in monitoring Alzheimer's Disease progression.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Kaye, Jeffrey a — Oregon Health & Science University
- Study coordinator: Kaye, Jeffrey a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.