Improving cognition and motivation in early psychosis treatment
Official title: Targeting Cognition and Motivation in Coordinated Specialty Care for Early Psychosis
Funded at University of Minnesota · NIH-10895269 · Data updated 2026-11-12
This study is looking to improve support for people dealing with early psychosis by using special care teams in Minnesota, focusing on personalized feedback and a mobile program to help with thinking and motivation over 12 weeks.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 1, 2019 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,251,514 |
| NIH project number | 5R01MH120589-05 |
| Project ID | NIH-10895269 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with early psychosis, particularly those experiencing cognitive and motivational impairments.
✕Less likely to help
Patients who do not have early psychosis or those whose cognitive and motivational functions are not significantly impaired may not benefit from this research.
What this research studies
This research aims to enhance psychiatric care for individuals experiencing early psychosis by implementing coordinated specialty care across six treatment teams in Minnesota. It focuses on using advanced measurement tools and informatics to track patient outcomes and evaluate the effectiveness of interventions. A key component involves personalized feedback sessions that target cognitive and motivational challenges, alongside a mobile intervention program designed to improve these areas over 12 weeks. The study seeks to address critical unmet needs in cognitive dysfunction and motivation among patients with early psychosis.
Why it matters
Potential benefit: If successful, this research could lead to improved cognitive function and motivation in patients with early psychosis, enhancing their overall treatment outcomes.
How similar studies have gone: Previous research has shown success in using mobile interventions for cognitive training in early schizophrenia, indicating potential for this approach.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Vinogradov, Sophia — University of Minnesota
- Study coordinator: Vinogradov, Sophia
Related research
Other NIH-funded projects on the same topics.
-
Social Cognition Measures for People at Risk of Psychosis
A study to find and test the best mental tasks that measure social thinking for people who might develop psychosis.
-
Using cerebellum-targeted brain stimulation to improve thinking in psychosis
Testing whether noninvasive brain stimulation of the cerebellum can help thinking and memory in people with psychotic illnesses like bipolar disorder or schizophrenia.
-
Social thinking tests for teens and young adults at risk for psychosis
This project is creating and checking social thinking tests for teens and young adults who show early signs of psychosis.
-
Evaluating social understanding in young people at risk for psychosis
This study is looking at how young people who might be at risk for psychosis understand social situations, so we can create better tools to help track their social skills over time and improve their care.
-
How the cerebellum affects thinking in people with psychosis
This study is looking at how a part of the brain called the cerebellum affects thinking problems in people with conditions like schizophrenia and bipolar disorder, and it hopes to find ways to improve these thinking skills using safe brain stimulation techniques.
-
Understanding how brain function affects social thinking in early psychosis
This study is looking at how the brain works when it comes to understanding other people's thoughts and feelings in people who are having their first episode of psychosis, and it hopes to find ways to help improve social skills and quality of life for them.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.