Improving clinical trials for neurological conditions in children and adults
Official title: Kennedy Krieger Institute - Johns Hopkins University NeuroNEXT Site
Funded at Hugo W. Moser Res Inst Kennedy Krieger · NIH-10885204 · Data updated 2026-11-12
This study is working to make it easier for kids and adults with neurological disorders to participate in clinical trials by simplifying the process and making sure their voices are heard, while also focusing on training new researchers and including a diverse group of participants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hugo W. Moser Res Inst Kennedy Krieger NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $427,108 |
| NIH project number | 5U24NS134009-02 |
| Project ID | NIH-10885204 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include children and adults with neurological disorders, particularly those who have not benefited from existing therapeutic interventions.
✕Less likely to help
Patients with neurological conditions that are already well-managed or for whom effective treatments are already available may not receive additional benefit from this research.
What this research studies
This research focuses on enhancing the effectiveness of clinical trials for neurological disorders affecting both children and adults. It aims to reduce barriers to early-phase clinical trials by utilizing a centralized Institutional Review Board and master trial agreements, which streamline the process. The initiative also emphasizes the importance of training the next generation of clinical trialists and integrating patient perspectives into trial design. By prioritizing pediatric populations and improving diversity among participants, the project seeks to foster community engagement and ensure that trials are more representative of the populations they aim to serve.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for neurological conditions, ultimately improving patient outcomes and quality of life.
How similar studies have gone: Previous research initiatives aimed at improving clinical trial processes have shown success in enhancing enrollment and diversity, indicating that this approach has potential for positive outcomes.
Where this research is happening
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Hugo W. Moser Res Inst Kennedy Krieger
Baltimore, United States Active
Researchers
- Principal investigator: Augustine, Erika — Hugo W. Moser Res Inst Kennedy Krieger
- Study coordinator: Augustine, Erika
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.