Improving circadian rhythms to support healthy aging
Concerted enhancement of core and output rhythms to promote healthy aging
This study looks at how our busy modern lives can throw off our natural body clocks and affect our health as we get older, and it explores how certain eating habits and a compound called Nobiletin might help improve our body rhythms and energy use, so you can learn ways to stay healthier as you age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10668956 on NIH RePORTER |
What this research studies
This research investigates how disruptions in natural circadian rhythms due to modern lifestyles can negatively impact health, particularly as we age. It explores the role of dietary interventions, such as time-restricted feeding and specific compounds like Nobiletin, in enhancing circadian rhythms and promoting better energy metabolism. By studying these effects, the research aims to identify ways to improve biological functions and reduce disease risk associated with aging. Patients may benefit from insights into dietary strategies that can help maintain their circadian health.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing disruptions in their sleep patterns or metabolic health.
Not a fit: Patients with stable circadian rhythms and no metabolic health issues may not receive significant benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that enhance circadian rhythms and promote healthier aging.
How similar studies have performed: Previous studies have shown that dietary interventions can positively influence circadian rhythms, suggesting a promising avenue for enhancing healthy aging.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Chen, Zheng — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Chen, Zheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.