Improving cholesterol management in young adults
Official title: Improving Lipid Management Strategies in Young Adults
Funded at Columbia University Health Sciences · NIH-11013428 · Data updated 2026-11-12
This study is looking at the best time to start cholesterol-lowering treatments for young adults aged 12 to 39 to help prevent heart disease, and it aims to create better tools to assess their risk by considering factors that affect their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 5, 2023 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $625,543 |
| NIH project number | 5R01HL168379-03 |
| Project ID | NIH-11013428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are young adults aged 12 to 39 with elevated low-density lipoprotein cholesterol (LDL-C) levels.
✕Less likely to help
Patients who are not within the age range of 12 to 39 or those with normal LDL-C levels may not benefit from this research.
What this research studies
This research focuses on understanding when to start lipid-lowering therapy in young adults to reduce the risk of atherosclerotic cardiovascular disease (ASCVD). It aims to develop better risk assessment tools that are applicable to younger populations, as current guidelines are primarily based on older adults. The study will evaluate the effectiveness of these new strategies in managing cholesterol levels and preventing heart disease in individuals aged 12 to 39. By incorporating social determinants of health, the research seeks to create a more comprehensive approach to lipid management.
Why it matters
Potential benefit: If successful, this research could lead to improved cholesterol management strategies that significantly reduce the risk of heart disease in young adults.
How similar studies have gone: Other research has shown success in developing risk assessment tools for older populations, but this approach for young adults is relatively novel.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Zhang, Yiyi — Columbia University Health Sciences
- Study coordinator: Zhang, Yiyi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.