Improving Childhood Asthma Care in Urban Communities
Childhood Asthma in Urban Settings Clinical Research Network - Leadership Center
This program tests prevention and treatment approaches—like giving helpful bacteria to infants and allergy immunotherapy—to help children with asthma who live in cities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11321105 on NIH RePORTER |
What this research studies
From a parent's perspective, researchers across a network of urban hospitals will run several linked projects to prevent and better treat childhood asthma. Some projects give immune-supporting bacteria to infants to try to reduce later allergy and asthma, while another tests cockroach allergy immunotherapy to improve control in allergic children. Teams will collect airway samples and use genetic and molecular (multi-omics) testing during flare-ups and clinic visits to find different asthma types and causes. The Leadership Center coordinates sites, enrollment, clinic visits, and data sharing so families can take part at nearby participating hospitals.
Who could benefit from this research
Good fit: Ideal participants are infants and children living in urban communities, including infants at high risk for asthma, children with cockroach-triggered allergic asthma, and children who have had severe exacerbations or ED visits.
Not a fit: Children without asthma or allergic triggers relevant to the protocols, or those unable to attend participating urban clinics, are unlikely to directly benefit from these specific studies.
Why it matters
Potential benefit: If successful, this work could prevent some cases of asthma, reduce severe attacks and emergency visits, and help match children to treatments that work best for their asthma type.
How similar studies have performed: Allergy immunotherapy has shown benefit for some allergic asthma, while microbiome-based prevention and multi-omics approaches are newer and have shown promising but still early and mixed results.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Jackson, Daniel J — University of Wisconsin-Madison
- Study coordinator: Jackson, Daniel J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.