Improving child heart health by reducing depression in pregnant women

Reducing maternal prenatal depression to improve child cardiovascular health

NIH-funded research University of Denver (Colorado Seminary) · NIH-11010864

This study is looking at how helping pregnant moms feel less depressed can lead to better heart health for their kids when they’re 3 to 4 years old, so if you're a mom-to-be dealing with depression, this research might be for you!

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Denver (Colorado Seminary) NIH-funded
Lab location1 site (Denver, United States)
Project IDNIH-11010864 on NIH RePORTER

What this research studies

This research investigates how reducing prenatal depression in mothers can positively impact the cardiovascular health of their children. By utilizing a randomized controlled trial, the study will implement a psychosocial intervention aimed at alleviating depressive symptoms in pregnant women. The researchers will track the health outcomes of children aged 3-4 years to determine if there is a significant improvement in cardiovascular health linked to the mother's mental health during pregnancy. This approach combines behavioral, physiological, and developmental analyses to understand the long-term effects of maternal mental health on child health.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women experiencing high levels of depressive symptoms.

Not a fit: Patients who are not pregnant or those without significant depressive symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cardiovascular health in children by addressing maternal mental health during pregnancy.

How similar studies have performed: Previous research has shown that interventions to reduce maternal depression can have positive effects on child health, suggesting potential success for this approach.

Where this research is happening

Denver, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.