Improving cervical cancer screening and treatment in low-resource settings
Official title: Research Project 2
Funded at Columbia University Health Sciences · NIH-10931485 · Data updated 2026-11-12
This study is looking at a new way to help women in South Africa get tested and treated for cervical cancer more easily and affordably, using a quick HPV test that can be done right in their local clinics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $179,287 |
| NIH project number | 5U54CA284030-02 |
| Project ID | NIH-10931485 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women living in low and middle-income countries, particularly those in public primary care settings who are at risk for cervical cancer.
✕Less likely to help
Patients who do not reside in low and middle-income countries or those who are not at risk for cervical cancer may not benefit from this research.
What this research studies
This research focuses on enhancing cervical cancer screening and treatment in low and middle-income countries, particularly through the implementation of HPV-based testing followed by immediate treatment. It aims to evaluate the costs and effectiveness of a new point-of-care HPV DNA test in public primary care settings in South Africa. By collaborating with local institutions, the project seeks to develop tailored strategies for the widespread adoption of this screening method, addressing both financial and operational challenges. The study will assess the cost-effectiveness of the screening process to ensure equitable access for women in these communities.
Why it matters
Potential benefit: If successful, this research could significantly reduce cervical cancer mortality rates among women in low-resource settings by improving access to effective screening and treatment.
How similar studies have gone: Previous research has shown success with similar HPV-based screening approaches, indicating potential for effective implementation in diverse settings.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Moodley, Jennifer Rose — Columbia University Health Sciences
- Study coordinator: Moodley, Jennifer Rose
Related research
Other NIH-funded projects on the same topics.
-
Precision phenotyping of emphysema in the elderly: a study in diverse adults
Researchers will look at CT scans and lung tests in older adults to understand different forms of emphysema and how they relate to health outcomes.
-
HPV-based cervical cancer screening and treatment implementation in resource-limited settings
A collaborative project to help doctors in South Africa put HPV-based screening and same-day treatment for cervical cancer into routine care, so more people get fast, effective care.
-
Cervical cancer screening and treatment rollout in resource-poor settings
A team from Columbia and the University of Cape Town is testing how to best implement affordable, same-day HPV-based screen-and-treat for cervical cancer in public health settings.
-
Understanding SCN3A-related Developmental Epileptic Encephalopathy and Finding Better Treatments
This NIH grant focuses on how SCN3A gene variants cause developmental epileptic encephalopathy and aims to develop more effective therapies for affected patients.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
M-CaRE: Mobile clinics and a smart heart-lung care tool for multimorbidity
A mobile, multilingual tool plus community health workers will help screen and manage high blood pressure and COPD in diverse adult patients, especially in underserved areas.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.