Improving cervical cancer screening and treatment for women living with HIV
CASCADE Coordinating Center
This project tries new ways to help women living with HIV get timely cervical cancer screening, follow-up care, and pre-cancer treatment in low-resource countries and underserved U.S. communities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Frontier Sci & Technology Rsch Fdn, INC NIH-funded |
| Lab location | 1 site (Amherst, UNITED STATES) |
| Project ID | NIH-11128504 on NIH RePORTER |
What this research studies
As a woman living with HIV, this network aims to put proven screening and treatment approaches into everyday clinics where I live. It will run practical clinical trials and coordinate sites to boost screening uptake, make sure people with positive screens get proper follow-up, and expand access to pre-cancer treatments. The coordinating center helps local clinics run the trials, manage data, and share successful approaches across sites in low- and middle-income countries and U.S. areas with health disparities. The goal is to test solutions that can be used widely in real-world, resource-constrained settings.
Who could benefit from this research
Good fit: Women living with HIV who are eligible for cervical cancer screening, especially those in low- and middle-income countries or in underserved U.S. communities, would be ideal candidates.
Not a fit: People who do not have a cervix, are not living with HIV, or who already have invasive cervical cancer are unlikely to directly benefit from these prevention-focused trials.
Why it matters
Potential benefit: If successful, the work could lower cervical cancer rates among women living with HIV by improving access to early detection and treatment.
How similar studies have performed: Screen-and-treat approaches and HPV-based screening have shown promise in other settings, but adapting and scaling these strategies specifically for women living with HIV and for resource-limited health systems is still being tested.
Where this research is happening
Amherst, UNITED STATES
- Frontier Sci & Technology Rsch Fdn, INC — Amherst, United States (Active)
Researchers
- Principal investigator: Siminski, Suzanne M. — Frontier Sci & Technology Rsch Fdn, INC
- Study coordinator: Siminski, Suzanne M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.