Improving cervical cancer outcomes by targeting specific bacteria
Targeting tumoral Lactobacillus iners to improve outcomes in cervical cancers
['FUNDING_R37'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10979840
This study is looking at how a certain bacteria called Lactobacillus iners, found in cervical tumors, might make cervical cancer harder to treat, and it hopes to find new ways to help women with advanced cervical cancer live longer and healthier lives.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10979840 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a specific bacteria, Lactobacillus iners, found in cervical tumors and its impact on treatment resistance in cervical cancer. The study aims to understand how this bacteria alters tumor metabolism and contributes to poor survival rates among patients. By exploring novel therapeutic approaches that target this bacteria, the research seeks to improve outcomes for women diagnosed with locally advanced cervical cancer. Patients may be involved in trials that assess new treatment strategies based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with locally advanced cervical cancer, particularly those who have not responded well to standard treatments.
Not a fit: Patients with early-stage cervical cancer or those who do not have the specific bacterial presence in their tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and survival rates for women with cervical cancer.
How similar studies have performed: While targeting tumor microbiomes is a novel approach, similar studies in other cancer types have shown promising results, indicating potential for success in this area.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COLBERT, LAUREN ELIZABETH — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: COLBERT, LAUREN ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.