Improving cell-based therapies for cancer treatment
CORE SUPPORT FOR THE IMMUNE CELL NETWORK
['FUNDING_OTHER'] · LEIDOS BIOMEDICAL RESEARCH, INC. · NIH-10502596
This study is working on improving special cell treatments that can help fight cancer and heal tissue damaged by radiation and chemotherapy, aiming to create personalized therapies that target tumors while keeping healthy cells safe, so they can be safely used in patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LEIDOS BIOMEDICAL RESEARCH, INC. (nih funded) |
| Locations | 1 site (FREDERICK, UNITED STATES) |
| Trial ID | NIH-10502596 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the engineering of various types of cells, such as stem cells and immune cells, to create effective treatments for cancer and tissue damage caused by radiation and chemotherapy. The approach involves developing personalized cell therapies that can target and destroy tumors while minimizing harm to healthy tissues. Researchers are addressing challenges related to the manufacturing and characterization of these 'living drugs' to ensure their safety and efficacy before they are used in patients. The goal is to advance the clinical application of these therapies and make them more widely available.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with hematologic malignancies or solid tumors who may benefit from innovative cell-based therapies.
Not a fit: Patients with non-cancerous conditions or those who do not have access to the specific cell therapies being developed may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments that improve patient outcomes.
How similar studies have performed: Previous research has shown promising results in the field of cell-based immunotherapies, indicating that this approach has the potential for significant advancements in cancer treatment.
Where this research is happening
FREDERICK, UNITED STATES
- LEIDOS BIOMEDICAL RESEARCH, INC. — FREDERICK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DMITROVSKY, ETHAN — LEIDOS BIOMEDICAL RESEARCH, INC.
- Study coordinator: DMITROVSKY, ETHAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer