Improving care to lower death rates in people with advanced HIV disease

An Enhanced Package of Care to Reduce Mortality in Persons with Advanced HIV Disease

['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-10896964

This study is looking to improve care for people with advanced HIV who have a low CD4 count by using new tests to quickly find and treat infections that can be dangerous for them, helping them live healthier lives.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-10896964 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing care for individuals with advanced HIV disease, particularly those with a CD4 count below 200 cells/µL. It aims to implement a comprehensive screening and prophylaxis package for opportunistic infections, which are common in this population. The study will utilize novel point-of-care diagnostics to identify patients and provide timely treatment, addressing the high mortality rates associated with advanced HIV. By validating this approach through clinical trials, the research seeks to improve patient outcomes and ensure better adherence to WHO recommendations.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who have a CD4 count of less than 200 cells/µL.

Not a fit: Patients with a CD4 count above 200 cells/µL or those who are not living with HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce mortality rates among individuals with advanced HIV disease by ensuring timely diagnosis and treatment of opportunistic infections.

How similar studies have performed: Previous research has shown that comprehensive care packages for HIV patients can lead to improved health outcomes, suggesting that this approach may also be effective.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.