Improving care for patients with opioid use disorder in emergency departments

The Emergency Department Longitudinal Integrated Care (ED-LINC) Effectiveness Randomized Trial Targeting Opioid Use and Related Comorbidity from the ED

NIH-funded research University of Washington · NIH-10868507

This study is testing a new way to help people with opioid use disorder who come to the emergency room by offering extra support and care, so they can feel better both right away and in the long run.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10868507 on NIH RePORTER

What this research studies

This research focuses on enhancing the treatment of patients with opioid use disorder (OUD) who visit emergency departments (EDs). It employs a multi-component intervention called the Emergency Department Longitudinal Integrated Care (ED-LINC), which includes overdose education, motivational support for outpatient care, and personalized medication management. By randomizing patients to receive either the ED-LINC intervention or standard care, the study aims to improve health outcomes for those struggling with OUD and related health issues. The approach is designed to provide comprehensive support during and after an ED visit, addressing both immediate and long-term healthcare needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are seeking treatment for opioid use disorder in emergency departments.

Not a fit: Patients who do not have opioid use disorder or are not seeking care in emergency departments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the management and outcomes of patients with opioid use disorder, reducing overdose risks and enhancing overall health.

How similar studies have performed: Previous research has shown promise in using collaborative care models for substance use disorders, indicating potential success for this approach.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.